*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CQ4005000
CHEMICAL NAME           : Barbituric acid, 5,5-dihydroxy- and nicotinamide
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C4-H4-N2-O5.C6-H6-N2-O
MOLECULAR WEIGHT        : 282.24
WISWESSER LINE NOTATION : T6VMVMV FHJ FQ FQ &T6NJ CVZ
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Alloxan monohydrate and nicotinamide
   * Nicotinamide and alloxan monohydrate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Multiple routes
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 345 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - changes in structure or function of endocrine pancreas
   Gastrointestinal - tumors
REFERENCE :
   ECJPAE Endocrinologia Japonica.  (Japan Pub. Trading Co., Ltd., POB 5030,
   Tokyo International, Tokyo, Japan)  V.1-    1954-  Volume(issue)/page/year:
   27,387,1980
 
                            *** END OF RECORD ***