*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CN1055000
CHEMICAL NAME           : Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,
                          1,1a,2,8b-tetrahydro-1,5-dimethyl-
                          8-(hydroxymethyl)-6-methoxy-, carbamate
CAS REGISTRY NUMBER     : 15973-07-6
OTHER CAS REGISTRY NOS. : 16033-17-3
BEILSTEIN REFERENCE NO. : 0768241
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H17-N3-O5
MOLECULAR WEIGHT        : 331.36
WISWESSER LINE NOTATION : T D3 B556 BN EN JV MVTT&&J E1 H1OVZ KO1 L1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Dedihydromitomycin B
   * 7-Methoxy-1,2-(N-methylaziridino)mitosene
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 19 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 14,103,1971
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 3 ug/L
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 20,767,1977
 
                            *** END OF RECORD ***