*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CN1056000
CHEMICAL NAME           : Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,
                          1,1a,2,8,8a,8b-hexahydro-8-
                          (hydroxymethyl)-6-isobutoxy-8a-methoxy-5-methyl-,
                          carbamate
CAS REGISTRY NUMBER     : 76079-86-2
LAST UPDATED            : 198606
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H25-N3-O6
MOLECULAR WEIGHT        : 391.47
WISWESSER LINE NOTATION : T D3 C556 EM HN JV MVTTT&J B1OVZ CO1 K1 LO1Y1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 9-(Hydroxymethyl)-7-isobutoxy-9a-methoxy-6-methylmitosane carbamate
   * 7-Isobutoxy-7-demethoxymitomycin A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3700 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 33,804,1980
 
                            *** END OF RECORD ***