*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CP1315000
CHEMICAL NAME           : Bactobolin
CAS REGISTRY NUMBER     : 72615-20-4
LAST UPDATED            : 199309
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H20-Cl2-N2-O6
MOLECULAR WEIGHT        : 383.26
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic BN 183B
   * (-)-Bactobolin
   * BN 183B
   * Y 12278
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6250 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 33,1054,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOPHDQ Journal of Pharmacobio-Dynamics.  (Japan Pub. Trading Co. (USA), 1255
   Howard St., San Francisco, CA 94103)  V.1-    1978- Volume(issue)/page/year:
   3,177,1980
 
                            *** END OF RECORD ***