*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CP0350000
CHEMICAL NAME           : Bacitracin A
CAS REGISTRY NUMBER     : 22601-59-8
LAST UPDATED            : 199512
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C66-H103-N17-O16-S
MOLECULAR WEIGHT        : 1422.92
WISWESSER LINE NOTATION : T5N CS AUTJ BYZY2 EVMY1Y&&VMY2VQVMYY2&&VM-WT-23-VM
                          DVM GVM JVM MVM QVMTJ C3Z FY2 I1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bacitracin F,  
   1-(N-((2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl)carbonyl)-L-leu  
   cine)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 158 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 6,417,1951
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 474 mg/kg/3D-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 6,417,1951
 
                            *** END OF RECORD ***