*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YX4004900
CHEMICAL NAME           : Venom, starfish, Acanthaster planci
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Acanthaster planci venom
   * Crown-of-thorns starfish
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 430 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - sensory change involving peripheral nerve
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 26,1077,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 170 ug/kg
TOXIC EFFECTS :
   Liver - jaundice, other or unclassified
   Liver - change in gall bladder structure or function
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 28,469,1990
 
                            *** END OF RECORD ***