*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZG1020000
CHEMICAL NAME           : Yohimban-16-alpha-carboxylic acid, 17-beta-hydroxy-,
                          methyl ester, hydrochloride
CAS REGISTRY NUMBER     : 75444-63-2
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H26-N2-O3.Cl-H
MOLECULAR WEIGHT        : 390.95
WISWESSER LINE NOTATION : T F6 D5 C666 EM ON&&TTTJ TQ UVO1 -17B
SYNONYMS/TRADE NAMES :
   * beta-Yohimbine hydrochloride
   * beta-Yohimbin hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   LDBU** "Zur Pharmakologie der Yohimbealkaloide, Dissertation," Langer, J.,
   Institute fuer Pharmakologie und Experimentelle Therapie der Universitat
   Breslau, Poland, 1932  Volume(issue)/page/year: -,-,1932
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   LDBU** "Zur Pharmakologie der Yohimbealkaloide, Dissertation," Langer, J.,
   Institute fuer Pharmakologie und Experimentelle Therapie der Universitat
   Breslau, Poland, 1932  Volume(issue)/page/year: -,-,1932
 
                            *** END OF RECORD ***