*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZF9340000
CHEMICAL NAME           : 3-beta,20-alpha-Yohimban-16-beta-carboxylic acid,
                          10-chloro-18-beta-hydroxy-17-alpha- methoxy-, methyl
                          ester, 3,4,5-trimethoxybenzoate (ester)
CAS REGISTRY NUMBER     : 7008-24-4
BEILSTEIN REFERENCE NO. : 0073937
REFERENCE               : 4-25-00-01284 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C32-H37-Cl-N2-O8
MOLECULAR WEIGHT        : 613.16
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 10-Chlorodeserpidine
   * Chloroserpidine
   * R 616
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 20 mg/kg
SEX/DURATION            : female 1-8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   15QWAW "Agents Affecting Fertility, a Symposium, 1964," Austin, C.R., and
   J.S. Perry, eds., Boston, Little, Brown & Co., 1965 Volume(issue)/page/year:
   -,290,1965
 
                            *** END OF RECORD ***