*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZE4650000
CHEMICAL NAME           : m-Xylene,
                          alpha,alpha,alpha,alpha',alpha',alpha'-hexachloro-
CAS REGISTRY NUMBER     : 881-99-2
BEILSTEIN REFERENCE NO. : 2214335
REFERENCE               : 4-05-00-00944 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C8-H4-Cl6
MOLECULAR WEIGHT        : 312.82
WISWESSER LINE NOTATION : GXGGR CXGGG
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Benzene, 1,3-bis(trichloromethyl)-
   * m-Bis(trichlormethyl)benzene
   * m-Bis(trichloromethyl)benzene
   * 1,3-Bis(trichloromethyl)benzene
   * 1,3-Di(trichloromethyl)benzene
   * alpha,alpha'-Hexachloro-m-xylene
   * alpha,alpha,alpha,alpha',alpha',alpha'-Hexachloroxylene
   * alpha,alpha,alpha,alpha',alpha',alpha'-Hexachloro-m-xylene
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg
REACTION SEVERITY       : Moderate
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,308,1969
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2924 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GNAMAP Gigiena Naselennykh Mest.  Hygiene in Populated Places. (Izdatel'stvo
   Zdorov'ya, Kiev, USSR) V.7-    1967- Volume(issue)/page/year: 21,34,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5700 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - altered sleep time (including change in righting reflex)
   Kidney, Ureter, Bladder - urine volume increased
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 29(11),51,1985
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2129 mg/kg
SEX/DURATION            : male 26 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   GNAMAP Gigiena Naselennykh Mest.  Hygiene in Populated Places. (Izdatel'stvo
   Zdorov'ya, Kiev, USSR) V.7-    1967- Volume(issue)/page/year: 21,34,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2129 mg/kg
SEX/DURATION            : female 26 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
   GNAMAP Gigiena Naselennykh Mest.  Hygiene in Populated Places. (Izdatel'stvo
   Zdorov'ya, Kiev, USSR) V.7-    1967- Volume(issue)/page/year: 21,34,1982
 
                            *** END OF RECORD ***