*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZD8400000
CHEMICAL NAME           : Xanthine, 3-hydroxy-, hydrate
CAS REGISTRY NUMBER     : 64038-49-9
LAST UPDATED            : 199706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C5-H4-N4-O3.H2-O
MOLECULAR WEIGHT        : 186.15
WISWESSER LINE NOTATION : T56 BM DN FNVMVJ FQ &QH
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 3-Hydroxyxanthine hydrate
   * 1H-Purine-2,6-dione, 3,7-dihydro-3-hydroxy-, monohydrate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 60 mg/kg/24W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   30,184,1970
 
                            *** END OF RECORD ***