*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ZA4870000
CHEMICAL NAME           : Virginiamycin S1,
                          4-(4(dimethylamino)-N-methyl-L-phenylalanine)-
CAS REGISTRY NUMBER     : 3131-03-1
BEILSTEIN REFERENCE NO. : 0078387
REFERENCE               : 4-27-00-09718 (Beilstein Handbook Reference)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C45-H54-N8-O10
MOLECULAR WEIGHT        : 867.07
WISWESSER LINE NOTATION : T F5-19-6 ANV DNV JNV MMV QOV TMV A&VTJ C1R DN1&1& D1
                          L2 P1 SR& OMV- BT6NJ CQ
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic 899
   * Antibiotic PA 114B
   * Antibiotic PA 114 B1
   * Mikamycin B
   * Mikamycin IA
   * Ostreogrycin B
   * PA 114B
   * Pristinamycin IA
   * Streptogramin B
   * Vernamycin BA
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
   Tokyo, Univ. of Tokyo Press, 1967  Volume(issue)/page/year: -,750,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,367,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds.,
   Tokyo, Univ. of Tokyo Press, 1967  Volume(issue)/page/year: -,750,1967
 
                            *** END OF RECORD ***