*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YY8180000
CHEMICAL NAME           : Vincaleukoblastine, O(sup
                          4)-deacetyl-3-de(methoxycarbonyl)-3-(2-hydroxyethylam
                          ino) carbonyl-, sulfate
CAS REGISTRY NUMBER     : 64234-48-6
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C45-H59-N5-O8.H2-O4-S
MOLECULAR WEIGHT        : 896.17
WISWESSER LINE NOTATION : T C6 B5665 2AB S BX IN QN NU JH&&TTTJ FO1 I1 KVM2Q KQ
                          LQ M2 E- NT F6 E596 A BN LM&TTTJ NVO1 R
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-beta-Hydroxyethyl-vds, sulfate salt
   * N-beta-Hydroxyethyl-vindesine, sulfate salt
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 22,391,1979
 
                            *** END OF RECORD ***