*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YX5425000
CHEMICAL NAME           : Veratric acid,
                          4-(ethyl(p-methoxy-alpha-methylphenethyl)amino)butyl
                          ester, hydrochloride
CAS REGISTRY NUMBER     : 2753-45-9
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C25-H35-N-O5.Cl-H
MOLECULAR WEIGHT        : 466.07
WISWESSER LINE NOTATION : 1OR BO1 DVO4N2&Y1&1R DO1 &GH
SYNONYMS/TRADE NAMES :
   * Csag-144
   * Duspatalin
   * 4-(Ethyl(p-methoxy-alpha-methylphenethyl)amino)butyl veratrate  
   hydrochloride
   * Mebeverine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1540 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2821584
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 17700 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2821584
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,338,1972
 
                            *** END OF RECORD ***