*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YX3969700
CHEMICAL NAME           : Venom, snake, Agkistrodon contortrix contortrix
LAST UPDATED            : 199109
DATA ITEMS CITED        : 4
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * A. contortrix contortrix venom
   * Agkistrodon contortrix controtrix venom
   * Southern copperhead venom
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 268 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBPBB8 Comparative Biochemistry and Physiology, B: Comparative Biochemistry.
    (Elsevier Science, 660 White Plans Rd., Tarrytown, NY 10591) V.38-    1971-
    Volume(issue)/page/year: 64,201,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 735 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBPBB8 Comparative Biochemistry and Physiology, B: Comparative Biochemistry.
    (Elsevier Science, 660 White Plans Rd., Tarrytown, NY 10591) V.38-    1971-
    Volume(issue)/page/year: 64,201,1979
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9520 ug/kg
TOXIC EFFECTS :
   Cardiac - pulse rate increase, without fall in BP
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   19DDA6 "Animal Toxins, a Collection of Papers Presented at the International
   Symposium on Animal Toxins, 1st, 1966," Russell, F.E., and P.R. Saunders,
   eds., New York, Pergamon Press Inc., 1967 Volume(issue)/page/year:
   -,269,1967
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 750 ug/kg
TOXIC EFFECTS :
   Cardiac - pulse rate increase, without fall in BP
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   19DDA6 "Animal Toxins, a Collection of Papers Presented at the International
   Symposium on Animal Toxins, 1st, 1966," Russell, F.E., and P.R. Saunders,
   eds., New York, Pergamon Press Inc., 1967 Volume(issue)/page/year:
   -,269,1967
 
                            *** END OF RECORD ***