*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YW2460000
CHEMICAL NAME           : Vanadium pentoxide (fume)
CAS REGISTRY NUMBER     : 1314-62-1
LAST UPDATED            : 199712
DATA ITEMS CITED        : 19
MOLECULAR FORMULA       : O5-V2
MOLECULAR WEIGHT        : 181.88
WISWESSER LINE NOTATION : .VA2.O5
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * RCRA waste number P120
   * Vanadium
   * Vanadium pentoxide, fume
   * Vanadium pentoxide, nonfused form, fume
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 27 ug/m3/24H/70D-C
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 31(7),8,1966
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 ug/m3/24H/17W-C
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in bladder weight
   Blood - changes in erythrocyte (RBC) count
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - monoamine oxidase
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 46(2),17,1981

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   85DHAX "Medical and Biologic Effects of Environmental Pollutants Series,"
   Washington, DC, National Academy of Sciences, 1972-77
   Volume(issue)/page/year: V,46,1974

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.05 mg/m3 (fume)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,275,1971

   OSHA PEL (Gen Indu):CL 0.1 mg(V2O5)/m3, fume
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):CL 0.1 mg(V2O5)/m3, fume
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):CL 0.1 mg(V2O5)/m3, fume
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):CL 0.1 mg(V2O5)/m3, fume
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

   OSHA PEL (Fed Cont):CL 0.5 mg(V2O5)/m3, dust
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO VANADIUM (as V2O5), resp dust/fume-air:CL 0.05 mg/m3/15M
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 76210
       No. of Facilities: 333 (estimated)
       No. of Industries: 7
       No. of Occupations: 12
       No. of Employees: 2562 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 76210
       No. of Facilities: 67 (estimated)
       No. of Industries: 6
       No. of Occupations: 17
       No. of Employees: 4468 (estimated)
       No. of Female Employees: 541 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   On EPA IRIS database
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Vanadium oxides, 7504
   
   NIOSH Analytical Method, 1996: Elements by ICP, 7300
   
   NTP Carcinogenesis studies; on test (two year studies), October 1997
   
   OSHA ANALYTICAL METHOD #ID-185

 
                            *** END OF RECORD ***