*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YV7380000
CHEMICAL NAME           : Valeric acid, 4,5-epoxy-3-hydroxy-, beta-lactone
CAS REGISTRY NUMBER     : 4247-30-7
BEILSTEIN REFERENCE NO. : 1305864
REFERENCE               : 5-19-04-00082 (Beilstein Handbook Reference)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C5-H6-O3
MOLECULAR WEIGHT        : 114.11
WISWESSER LINE NOTATION : T4OVTJ D- BT3OTJ
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 4,5-Epoxy-3-hydroxyvaleric acid-beta-lactone
   * Pentanoic acid, 4,5-epoxy-3-hydroxy-, beta-lactone
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 76 gm/kg/63W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   35,707,1965
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 88 gm/kg/73W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   14JTAF "Mycotoxins in Foodstuffs, Proceedings of the Symposium held at the
   Massachusetts Institute of Technology, 1964," Wogan, G.N., ed., Cambridge,
   MA, MIT Press, 1965  Volume(issue)/page/year: -,275,1965
 
                            *** END OF RECORD ***