*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YU7050080
CHEMICAL NAME           : Uric acid
CAS REGISTRY NUMBER     : 69-93-2
LAST UPDATED            : 199710
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C5-H4-N4-O3
MOLECULAR WEIGHT        : 168.13
COMPOUND DESCRIPTOR     : Mutagen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 7,9-Dihydro-1H-purine-2,6,8(3H)-trione
   * Lithic acid
   * 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-
   * 2,6,8-Trihydroxypurine
   * 2,6,8-Trioxopurine
   * 2,6,8-Trioxypurine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5040 mg/kg
SEX/DURATION            : male 4 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 32,36,1985
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK)  V.1- 1969- 
   Volume(issue)/page/year: 4,87,1971

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 82048
       No. of Facilities: 246 (estimated)
       No. of Industries: 5
       No. of Occupations: 4
       No. of Employees: 2320 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 82048
       No. of Facilities: 1210 (estimated)
       No. of Industries: 5
       No. of Occupations: 8
       No. of Employees: 17397 (estimated)
       No. of Female Employees: 12409 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***