*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YT9950400
CHEMICAL NAME           : Urea,
                          1-(alpha-(4-oxo-2-phenyl-3,4-dihydro-3-quinazolinyl)h
                          ydrocinnamoyl)-3-(o-t olyl)-2-thio-
CAS REGISTRY NUMBER     : 72045-81-9
BEILSTEIN REFERENCE NO. : 0732821
REFERENCE               : 5-24-04-00219 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C31-H26-N4-O2-S
MOLECULAR WEIGHT        : 518.67
WISWESSER LINE NOTATION : T66 BVN ENJ CY1R&VMYUS&MR B1& DR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-(alpha-(4-Oxo-2-phenyl-3,4-dihydro-3-quinazolinyl)hydrocinnamoyl)-3-(o
     -tolyl)-2-thiourea
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   31,161,1979
 
                            *** END OF RECORD ***