*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YT8205000
CHEMICAL NAME           : Urea, 1-methyl-1-nitroso-3-(p-tolyl)-
CAS REGISTRY NUMBER     : 23139-00-6
BEILSTEIN REFERENCE NO. : 2939628
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H11-N3-O2
MOLECULAR WEIGHT        : 193.23
WISWESSER LINE NOTATION : ONN1&VMR D1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-Methyl-N'-(p-methylphenyl)-N-nitrosourea
   * 1-Methyl-1-nitroso-3-(p-tolyl)urea
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 574 mg/kg/7W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   44,1027,1984
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 33500 pmol/plate
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,5147,1979
 
                            *** END OF RECORD ***