*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YT3978332
CHEMICAL NAME           : Urea,
                          N-(3-(3-(4-fluorophenoxy)phenyl)-1-methyl-2-propenyl)
                          -N-hydroxy-, (R-(E))-
CAS REGISTRY NUMBER     : 132339-70-9
LAST UPDATED            : 199603
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H17-F-N2-O3
MOLECULAR WEIGHT        : 316.36
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 225C
   * N-(3-(3-(4-Fluorophenoxy)phenyl)-1-methyl-2-propenyl)-N-hydroxyurea  
   (R-(E))-
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 700 mg/kg/14D-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Kidney, Ureter, Bladder - interstitial nephritis
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   69,480,1995
 
                            *** END OF RECORD ***