*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YS9826000
CHEMICAL NAME           : Urea,
                          1-(3,4-dihydro-4-oxo-3-quinazolinylmethyl)-3-(4-pheny
                          lpiperidinoacetyl)-, tetrahydrochloride
CAS REGISTRY NUMBER     : 70395-23-2
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H25-N5-O3.4Cl-H
MOLECULAR WEIGHT        : 565.37
WISWESSER LINE NOTATION : T66 BVN ENJ C1MVMV1- AT6NTJ DR &GH 4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-(3,4-Dihydro-4-oxo-3-quinazolinylmethyl)-3-(4-phenylpiperidinoacetyl)u
     rea 4HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   IJSIDW Indian Journal of Pharmaceutical Sciences.  (Kalina, Santa Cruz
   (East), Bombay 400 029, India)  V.40(2)-    1978-  Volume(issue)/page/year:
   41,33,1979
 
                            *** END OF RECORD ***