*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YT0195000
CHEMICAL NAME           : Urea, 1,1-dimethyl-3-(5-methyl-2-benzimidazolyl)-,
                          hydrochloride, hydrate
CAS REGISTRY NUMBER     : 64022-49-7
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H14-N4-O.Cl-H.H2-O
MOLECULAR WEIGHT        : 272.77
WISWESSER LINE NOTATION : T56 BM DNJ CMVN1&1 G1 &GH &QH
COMPOUND DESCRIPTOR     : Mutagen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 1,1-Dimethyl-3-(5-methyl-2-benzimidazolyl)urea hydrochloride hydrate
   * U-32.422E
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 75 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   ANDRDQ Andrologia.  (Grosse Verlag GmbH, Kurfuerstenstr. 112-113, D-1000
   Berlin 30, Fed. Rep. Ger.) V.6-    1974-  Volume(issue)/page/year:
   6,245,1974
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 75 mg/kg
REFERENCE :
   ANDRDQ Andrologia.  (Grosse Verlag GmbH, Kurfuerstenstr. 112-113, D-1000
   Berlin 30, Fed. Rep. Ger.) V.6-    1974-  Volume(issue)/page/year:
   6,245,1974
 
                            *** END OF RECORD ***