*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM6770000
CHEMICAL NAME           : 1-Aziridinecarboxamide, N-(p-methoxyphenyl)-
CAS REGISTRY NUMBER     : 3647-17-4
BEILSTEIN REFERENCE NO. : 1344474
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H12-N2-O2
MOLECULAR WEIGHT        : 192.24
WISWESSER LINE NOTATION : T3NTJ AVMR DO1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 1-(1-Aziridinyl)-N-(p-methoxyphenyl)formamide
   * Formamide, 1-(1-aziridinyl)-N-(p-methoxyphenyl)-
   * N-(p-Methoxyphenyl)-1-aziridinecarboxamide
   * p-Methoxyphenyl-N-carbamoylaziridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#03949
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 240 mg/kg/4W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   29,2184,1969
 
                            *** END OF RECORD ***