*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM4100000
CHEMICAL NAME           : 2H-Azepin-2-one, hexahydro-5,5,7-trimethyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 66968-17-0
LAST UPDATED            : 199210
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H7-N-O.Cl-H
MOLECULAR WEIGHT        : 181.63
WISWESSER LINE NOTATION : T7MVTJ E1 E1 G1
SYNONYMS/TRADE NAMES :
   * Hexahydro-5,5,7-trimethyl-2H-azepin-2-one hydrochloride
   * Trimethylhexanone isoxime hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 136 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
   Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
    Volume(issue)/page/year: 50,199,1903
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 407 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - muscle weakness
   Behavioral - ataxia
REFERENCE :
   AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie.  (Leipzig,
   Ger. Dem. Rep.)  V.1-109, 1873-1925.  For publisher information, see NSAPCC.
    Volume(issue)/page/year: 50,199,1903
 
                            *** END OF RECORD ***