*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM3552000
CHEMICAL NAME           : Azepino(4,5-b)indole,
                          1,2,3,4,5,5a,6,10b-octahydro-3,9-dimethyl-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 19971-17-6
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H18-N2.2Cl-H
MOLECULAR WEIGHT        : 287.26
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Carazedine
   * 1,2,3,4,5,5a,6,10b-Octahydro-3,9-dimethylazepino(4,5-b)indole  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EKFAE9 Eksperimental'naya i Klinicheskaya Farmakologiya.  Experimental and
   Clinical Pharmacology. (Mezhdunarodnaya Kniga, ul. B. Yakimanka, 39, 117049
   Moscow, Russia)  V.55-    1992-  Volume(issue)/page/year: 57(2),4,1994
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EKFAE9 Eksperimental'naya i Klinicheskaya Farmakologiya.  Experimental and
   Clinical Pharmacology. (Mezhdunarodnaya Kniga, ul. B. Yakimanka, 39, 117049
   Moscow, Russia)  V.55-    1992-  Volume(issue)/page/year: 57(2),4,1994
 
                            *** END OF RECORD ***