*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CM3286000
CHEMICAL NAME           : 1H-Azepine,
                          hexahydro-1-methyl-4-((2-methyl-6,11-dihydrodibenzo(b
                          ,e)thiepin-11-yl)oxy) -, maleate (1:1)
LAST UPDATED            : 198710
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H27-N-O-S.C4-H4-O4
MOLECULAR WEIGHT        : 469.64
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   Hexahydro-1-methyl-4-((2-methyl-6,11-dihydrodibenzo(b,e)thiepin-11-yl)ox
     y)-1H-azepine maleate
   *   2-Methyl-11-(1-methylperhydroazepin-4-yloxy)-6,11-dihydrodibenzo(b,e)thi
     epin hydrogen maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 345 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 51,2034,1986
 
                            *** END OF RECORD ***