*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CL5615930
CHEMICAL NAME           : 8-Azabicyclo(3.2.1)octane,
                          3-(diphenylmethoxy)-8-(1-methylethyl)-, hydrochloride
CAS REGISTRY NUMBER     : 15386-00-2
LAST UPDATED            : 199412
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H29-N-O.Cl-H
MOLECULAR WEIGHT        : 371.99
SYNONYMS/TRADE NAMES :
   * 3-(Diphenylmethoxy)-8-isopropylnortropan hydrochloride
   * 3-(Diphenylmethoxy)-8-(1-methylethyl)-8-azabicyclo(3.2.1)octane  
   hydrochloride
   * Nortropane, 3-(diphenylmethoxy)-8-isopropyl-, hydrochloride
   * Sch 221 hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 65 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,876,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 47 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 17,876,1967
 
                            *** END OF RECORD ***