*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CL5603190
CHEMICAL NAME           : 8-Azabicyclo(3.2.1)octane-3-carboxylic acid,
                          8-methyl-2-(2-thienyl)-, methyl ester, hydrochloride,
                          (1R-(exo,exo))-
CAS REGISTRY NUMBER     : 68398-25-4
LAST UPDATED            : 199009
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H19-N-O2-S.Cl-H
MOLECULAR WEIGHT        : 301.86
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (-)-Methyl  
   (1RS-exo,exo)-8-methyl-2-(2-thienyl)-8-azabicyclo(3.2.1)octane-3-carboxy  
   late HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 21,1243,1978
 
                            *** END OF RECORD ***