*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CL5603100
CHEMICAL NAME           : 8-Azabicyclo(3.2.1)octane-2-carboxylic acid,
                          8-methyl-3-phenyl-, methyl ester, (exo,exo)-
CAS REGISTRY NUMBER     : 74163-84-1
LAST UPDATED            : 198611
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H21-N-O2
MOLECULAR WEIGHT        : 259.38
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-beta-Methoxycarbonyl-3-beta-phenyltropane
   * (exo,exo)-8-Methyl-3-phenyl-8-azabicyclo(3.2.1)octane-2-carboxylic acid  
   methyl ester
   * Troparil
   * WIN 35065
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 185 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 48(1),15,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 48,26,1985
 
                            *** END OF RECORD ***