*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : CL5603050
CHEMICAL NAME           : 2-Azabicyclo(2.2.2)octane-6-endo-carboxylic acid,
                          2-methyl-6-phenyl-, ethyl ester, monohydrochloride
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H23-N-O2.Cl-H
MOLECULAR WEIGHT        : 309.87
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Methyl-6-phenyl-2-azabicyclo(2.2.2)octane-6-endo-carboxylic acid ethyl  
   ester hydrochloride
   * 2-Methyl-6-exo-phenyl-6-endo-carbethoxy-2-azabicyclo(2.2.2)octane  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 149 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - excitement
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 22,1,1987
 
                            *** END OF RECORD ***