*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YS5014450
CHEMICAL NAME           : Urea, 1-(2-chloroethyl)-3-morpholino-1-nitroso-
CAS REGISTRY NUMBER     : 72122-60-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C7-H14-Cl-N4-O3
MOLECULAR WEIGHT        : 237.70
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 1-(2-Chloroethyl)-3-morpholino-1-nitrosourea
   * Morpholino-cnu
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 32 mg/kg/60W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Gastrointestinal - tumors
REFERENCE :
   DTESD7 52 Vanderbilt Ave., New York, NY 10017)  V.1-15, 1977-87.
   Discontinued 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1977-
   Volume(issue)/page/year: 8,273,1980
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 51 mg/kg/24W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Gastrointestinal - tumors
REFERENCE :
   DTESD7 52 Vanderbilt Ave., New York, NY 10017)  V.1-15, 1977-87.
   Discontinued 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1977-
   Volume(issue)/page/year: 8,273,1980
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 64 mg/kg/60W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Gastrointestinal - tumors
REFERENCE :
   DTESD7 52 Vanderbilt Ave., New York, NY 10017)  V.1-15, 1977-87.
   Discontinued 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1977-
   Volume(issue)/page/year: 8,273,1980
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 102 mg/kg/24W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Gastrointestinal - tumors
REFERENCE :
   DTESD7 52 Vanderbilt Ave., New York, NY 10017)  V.1-15, 1977-87.
   Discontinued 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1977-
   Volume(issue)/page/year: 8,273,1980
 
                            *** END OF RECORD ***