*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YS4987990
CHEMICAL NAME           : Urea,
                          N'-(2-chloroethyl)-N-(2-hydroxypropyl)-N-nitroso-
CAS REGISTRY NUMBER     : 96806-35-8
BEILSTEIN REFERENCE NO. : 5935513
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H12-Cl-N3-O3
MOLECULAR WEIGHT        : 209.66
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N'-(2-Chloroethyl)-N-(2-hydroxypropyl)-N-nitrosourea
   * CPNU-I
   * 1-Nitroso-1-hydroxypropyl-3-chloroethylurea
   * 1-Nitroso-1-(2-hydroxypropyl)-3-(2-chloroethyl)urea
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1104 mg/kg/30W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
REFERENCE :
   JCROD7 Journal of Cancer Research and Clinical Oncology.  (Springer-Verlag
   New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.93-
   1979-  Volume(issue)/page/year: 112,221,1986
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 50 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 178,157,1987
 
                            *** END OF RECORD ***