*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YS4980800
CHEMICAL NAME           : Urea,
                          1-(2-chloroethyl)-3-(D-glucopyranos-3-yl)-1-nitroso-
CAS REGISTRY NUMBER     : 73237-82-8
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C9-H16-Cl-N3-O7
MOLECULAR WEIGHT        : 313.73
WISWESSER LINE NOTATION : T6OTJ BQ CQ DOMVNNO&2G EQ F1Q
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * 1-(2-Chloroethyl)-3-(D-glucos-3-yl)-1-nitrosourea
   * D-Glucose, 3-((((2-chloroethyl)nitrosoamino)carbonyl)amino)-
   * KCNU
   * NSC 319735D
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Endocrine - diabetes mellitus
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 33,517,1980
 
                            *** END OF RECORD ***