*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YS4552800
CHEMICAL NAME           : Urea,
                          1-(carbamoylmethyl)-3-(2-chloroethyl)-1-methyl-3-nitr
                          oso-
CAS REGISTRY NUMBER     : 81965-43-7
LAST UPDATED            : 198909
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H11-Cl-N4-O3
MOLECULAR WEIGHT        : 222.66
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(Carbamoylmethyl)-3-(2-chloroethyl)-1-methyl-3-nitrosourea
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 392 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 25,829,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 427 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 25,829,1982
 
                            *** END OF RECORD ***