*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YS2717000
CHEMICAL NAME           : Urea,
                          N-(1,3-bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)
                          -N,N'-bis(hydroxymeth yl)-
CAS REGISTRY NUMBER     : 78491-02-8
LAST UPDATED            : 199806
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C8-H14-N4-O7
MOLECULAR WEIGHT        : 278.26
SYNONYMS/TRADE NAMES :
   *   N-(1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-N,N'-bis(hydroxyme
     thyl)urea
   * Diazolidinyl urea
   * Germall 11
   *   N-(Hydroxymethyl)-N-(1,3-dihydroxymethyl-2,5-dioxo-4-imidazolidinyl)-N'-
     (hydroxymethyl)urea
   * Imidazolidinyl urea 11
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 9(2),229,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3573 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - ataxia
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   JTOTDO Journal of Toxicology, Cutaneous and Ocular Toxicology.  (Marcel
   Dekker, 270 Madison Ave., New York, NY 10016)  V.1-    1982-
   Volume(issue)/page/year: 14,3,1995
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   JTOTDO Journal of Toxicology, Cutaneous and Ocular Toxicology.  (Marcel
   Dekker, 270 Madison Ave., New York, NY 10016)  V.1-    1982-
   Volume(issue)/page/year: 14,3,1995
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : >2250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JTOTDO Journal of Toxicology, Cutaneous and Ocular Toxicology.  (Marcel
   Dekker, 270 Madison Ave., New York, NY 10016)  V.1-    1982-
   Volume(issue)/page/year: 14,3,1995
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 11200 mg/kg/7D-I
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 9(2),229,1990
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 26100 mg/kg/29D-I
TOXIC EFFECTS :
   Gastrointestinal - gastritis
   Endocrine - changes in adrenal weight
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 9(2),229,1990

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X2520
       No. of Facilities: 429 (estimated)
       No. of Industries: 2
       No. of Occupations: 3
       No. of Employees: 6467 (estimated)
       No. of Female Employees: 6039 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***