*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YR6555950
CHEMICAL NAME           : Urea,
                          N'-(3-acetyl-4-(3-((1,1-dimethylethyl)amino)-2-hydrox
                          ypropoxy)phenyl)-N,N- diethyl-, monohydrochloride,
                          (R)-
CAS REGISTRY NUMBER     : 125638-91-7
LAST UPDATED            : 199110
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H33-N3-O4.Cl-H
MOLECULAR WEIGHT        : 416.02
SYNONYMS/TRADE NAMES :
   *   (+)-3-(3-Acetyl-4-(3-(tert-butylamino)-2-hydroxypropoxy)phenyl)-1,1-diet
     hylurea hydrochloride
   * NBP-584
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1014 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 38,295,1989
 
                            *** END OF RECORD ***