*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YP0480000
CHEMICAL NAME           : Tylosin, 4(sup
                          A)-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyran
                          osyl)-3(sup C)-O- demethyl-
CAS REGISTRY NUMBER     : 11049-05-1
LAST UPDATED            : 199309
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C38-H63-N-O14
MOLECULAR WEIGHT        : 758.02
WISWESSER LINE NOTATION : T-16-OV JV KU MUTJ DQ E1 G1VH I1 M1 P2 FO- BT6OTJ CQ
                          DN1&1 EQ F1& O1O- BT6OTJ CO1 DQ EQ F1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Demycarosylmacrocin
   * Lactenocin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 2,137,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 2,137,1980
 
                            *** END OF RECORD ***