*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YM4375800
CHEMICAL NAME           : 1-alpha-H,5-alpha-H-Tropan-3-beta-ol,
                          cyclohexylacetate (ester), hydrochloride
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H27-N-O2.Cl-H
MOLECULAR WEIGHT        : 301.90
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * psi-Tropine cyclohexylacetate hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   8,88,1966
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   8,88,1966
 
                            *** END OF RECORD ***