*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : YK4570000
CHEMICAL NAME : Triphosphoric acid, pentasodium salt
CAS REGISTRY NUMBER : 7758-29-4
LAST UPDATED : 199712
DATA ITEMS CITED : 15
MOLECULAR FORMULA : O10-P3.5Na
MOLECULAR WEIGHT : 367.86
WISWESSER LINE NOTATION : NA5 P3-O5
SYNONYMS/TRADE NAMES :
* Armofos
* Empiphos stp-D
* Natriumtripolyphosphat
* Pentasodium triphosphate
* Pentasodium tripolyphosphate
* Polygon
* Rhodiaphos LV
* S 400
* Sodium phosphate (Na5P3O10)
* Sodium triphosphate
* Sodium triphosphate (Na5P3O10)
* Sodium tripolyphosphate
* STPP
* Thermphos
* Thermphos L 50
* Thermphos N
* Thermphos SPR
* Tripoly
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3120 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - coma
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0545589
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 525 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 108,117,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2060 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VLUBB6 Vestnik Leningradskogo Universiteta, Biologiya. Journal of Leningrad
University, Biology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1-
1956- Volume(issue)/page/year: (3),97,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3100 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 38(9),19,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 700 mg/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
REFERENCE :
REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique. (Masson
Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France) V.1-
1953- Volume(issue)/page/year: 10,391,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 7,445,1957
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 71 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 7,445,1957
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VLUBB6 Vestnik Leningradskogo Universiteta, Biologiya. Journal of Leningrad
University, Biology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1-
1956- Volume(issue)/page/year: (3),97,1984
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2730 mg/kg/13W-I
TOXIC EFFECTS :
Endocrine - changes in spleen weight
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 38(9),19,1973
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 80076
No. of Facilities: 101624 (estimated)
No. of Industries: 308
No. of Occupations: 153
No. of Employees: 930493 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 80076
No. of Facilities: 49146 (estimated)
No. of Industries: 268
No. of Occupations: 169
No. of Employees: 943961 (estimated)
No. of Female Employees: 347961 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8786;8EHQ-0892-8869
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***