*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ5625000
CHEMICAL NAME           : s-Triazolo(4,3-a)pyridine,
                          5,6,7,8-tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)et
                          hyl)-, hydrochloride
CAS REGISTRY NUMBER     : 72822-12-9
LAST UPDATED            : 199009
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H27-N5.Cl-H
MOLECULAR WEIGHT        : 361.97
WISWESSER LINE NOTATION : T56 AN CNN&TJ B2- AT6N DNTJ DR B1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AF 2139
   * Dapiprazol
   * Dapiprazole
   * Glamidolo
   * Reversil
   *   5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3
     -a)pyridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - miosis (pupillary constriction)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 32,668,1982
 
                            *** END OF RECORD ***