*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ5478470
CHEMICAL NAME           : 1,2,4-Triazolo(3,4-a)isoquinoline,
                          5,6-dihydro-8,9-dimethoxy-
CAS REGISTRY NUMBER     : 35515-48-1
BEILSTEIN REFERENCE NO. : 0887453
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C12-H13-N3-O2
MOLECULAR WEIGHT        : 231.28
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5,6-Dihydro-8,9-dimethoxy-1,2,4-triazolo(3,4-a)isoquinoline
   * 8,9-Dimethoxy-3,4-dihydro(1,2,4)triazolo(3,4-a)isoquinoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 285 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - tremor
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,324,1981
 
                            *** END OF RECORD ***