*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ5469570
CHEMICAL NAME           : 4-Thiazolin-2-one,
                          3-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-4-phen
                          yl-, dihydrochloride, hydrate
CAS REGISTRY NUMBER     : 109758-41-0
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C29-H31-N3-O-S.2Cl-H.H2-O
MOLECULAR WEIGHT        : 559.62
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(3-(4-(Diphenylmethyl)-1-piperazinyl)propyl)-4-phenyl-4-thiazolin-2-one 
    dihydrochloride H2O
   * M.G. 16055
   * 2(3H)-Thiazolone,  
   3-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-4-phenyl-, 2HCl H2O
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 42,359,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 42,359,1987
 
                            *** END OF RECORD ***