*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ5359160
CHEMICAL NAME           : 3H-1,2,4-Triazole-3-thione,
                          2,4-dihydro-5-((2-methyl-1H-indol-3-yl)methyl)-4-phen
                          yl-
CAS REGISTRY NUMBER     : 54648-98-5
BEILSTEIN REFERENCE NO. : 4533419
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H16-N4-S
MOLECULAR WEIGHT        : 320.44
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2,4-Dihydro-5-((2-methyl-1H-indol-3-yl)methyl)-4-phenyl-3H-1,2,4-triazol
     e-3-thione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   CNJPAZ Canadian Journal of Pharmaceutical Sciences.  (Toronto, Ont., Canada)
    V.1-16, 1966-81. Discontinued.  Volume(issue)/page/year: 9,108,1974
 
                            *** END OF RECORD ***