*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XY7355000
CHEMICAL NAME           : s-Triazine,
                          1,2-dihydro-1-(p-chlorophenyl)-4,6-diamino-2,2-dimeth
                          yl-
CAS REGISTRY NUMBER     : 516-21-2
BEILSTEIN REFERENCE NO. : 0229760
REFERENCE               : 4-26-00-01176 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H14-Cl-N5
MOLECULAR WEIGHT        : 251.75
WISWESSER LINE NOTATION : T6N CN EN BHJ AR DG& B1 B1 DZ FZ
COMPOUND DESCRIPTOR     : Mutagen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 4-Amino-6-p-chloroanilino-1,2-dwuhydro-2,2-dwumethylo-1,3,5-trojazyna
   * Chlorguanide triazine
   * CGT
   * 1-(p-Chlorophenyl)-4,6-diamino-2,2-dimethyl-1,2-dihydro-s-triazine
   * 1-p-Chlorophenyl-1,2-dihydro-2,2-dimethyl-4,6-diamino-s-triazine
   * Cycloguanil
   * Cycloguanyl
   * 1,3,5-Triazine-2,4-diamine, 1,6-dihydro-1-(4-chlorophenyl)-6,6-dimethyl-
   * WR 5473
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 98 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 10,81,1958
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 50 mg/kg
SEX/DURATION            : female 1 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   BEBMAE Byulleten' Eksperimental'noi Biologii i Meditsiny.  Bulletin of
   Experimental Biology and Medicine.  For English translation, see BEXBAN.
   (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 77(6),56,1974
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   AMACCQ Antimicrobial Agents and Chemotherapy.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.1-    1972-
   Volume(issue)/page/year: 12,84,1977
 
                            *** END OF RECORD ***