*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XY3215000
CHEMICAL NAME           : as-Triazine, 3-amino-6-(2-(5-nitro-2-furyl)vinyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 15461-22-0
LAST UPDATED            : 199709
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C9-H7-N5-O3.Cl-H
MOLECULAR WEIGHT        : 269.67
WISWESSER LINE NOTATION : T6NN DNJ CZ F1U1- BT5OJ ENW &GH
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 3-Amino-6-(2-(5-nitro-2-furyl)vinyl)-as-triazine, hydrochloride
   * 6-(5-Nitro-2-furylvinyl)-3-amino-1,2,4-triazine hydrochloride
   * Panfuran hydrochloride
   * 1,2,4-Triazin-3-amine, 6-(2-(5-nitro-2-furanyl)ethenyl)-,  
   monohydrochloride
   * as-Triazine, 3-amino-6-(2-(5-nitro-2-furyl)vinyl)-, monohydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PMDCAY Progress in Medical Chemistry.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1961- Volume(issue)/page/year:
   5,320,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PMDCAY Progress in Medical Chemistry.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1961- Volume(issue)/page/year:
   5,320,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PMDCAY Progress in Medical Chemistry.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1961- Volume(issue)/page/year:
   5,320,1967
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 200 ug/L
REFERENCE :
   BBACAQ Biochimica et Biophysica Acta.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1947- Volume(issue)/page/year:
   68,502,1963
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 100 ug/L
REFERENCE :
   BBACAQ Biochimica et Biophysica Acta.  (Elsevier Science Pub. B.V., POB 211,
   1000 AE Amsterdam, Netherlands)  V.1-    1947- Volume(issue)/page/year:
   68,502,1963
 
                            *** END OF RECORD ***