*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XW5869600
CHEMICAL NAME           : Toxin, plethodontid salamander, tetrodotoxin, skin
                          extract
LAST UPDATED            : 198112
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * TIX
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 19,25,1981
 
                            *** END OF RECORD ***