*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XO8590000
CHEMICAL NAME           : Threonine, L-
CAS REGISTRY NUMBER     : 72-19-5
LAST UPDATED            : 199709
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C4-H9-N-O3
MOLECULAR WEIGHT        : 119.14
WISWESSER LINE NOTATION : QY1&YZVQ -L
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Threonin
   * Threonine
   * L-Threonine
   * (S)-Threonine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3098 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   ABBIA4 Archives of Biochemistry and Biophysics.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.31-    1951-  Volume(issue)/page/year:
   58,253,1955
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 372,75,1996

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 81868
       No. of Facilities: 53 (estimated)
       No. of Industries: 1
       No. of Occupations: 3
       No. of Employees: 750 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 81868
       No. of Facilities: 787 (estimated)
       No. of Industries: 3
       No. of Occupations: 13
       No. of Employees: 18524 (estimated)
       No. of Female Employees: 13980 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***