*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XU3685000
CHEMICAL NAME           : o-Toluidine, N,N-bis(2-chloroethyl)-5-nitro-
CAS REGISTRY NUMBER     : 21447-45-0
BEILSTEIN REFERENCE NO. : 3100261
REFERENCE               : 4-12-00-01808 (Beilstein Handbook Reference)
LAST UPDATED            : 199707
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H14-Cl2-N2-O2
MOLECULAR WEIGHT        : 277.17
WISWESSER LINE NOTATION : WNR D1 CN2G2G
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzenamine, N,N-bis(2-chloroethyl)-2-methyl-5-nitro-
   * N,N-Bis(2-chloroethyl)-5-nitro-o-toluidine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CTRRDO Cancer Treatment Reports.  (Washington, DC)  V.60-71, 1976-87.  For
   publisher information,  see JNCIEQ.  Volume(issue)/page/year: 62,2045,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 12,161,1969
 
                            *** END OF RECORD ***