*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XU1590000
CHEMICAL NAME           : o-Toluic acid, 5-bis(2-chloroethyl)amino-
CAS REGISTRY NUMBER     : 5977-36-6
BEILSTEIN REFERENCE NO. : 3119531
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C12-H15-Cl2-N-O2
MOLECULAR WEIGHT        : 276.18
WISWESSER LINE NOTATION : QVR B1 EN2G2G
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acidul 5,N,N-di-(2-cloretil)amino-2-metilbenzoic
   * Benzoic acid, 5-bis(2-chloroethyl)amino-2-methyl-
   * 5-Bis(2-chloroethyl)amino-2-methylbenzoic acid
   * 5-Bis(2-chloroethyl)amino-o-toluic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 62 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRMBAZ Farmacia (Bucharest).  (Rompresfilatelia, POB 12-201, Bucharest,
   Romania)  V.1-    1953-  Volume(issue)/page/year: 15,103,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 62 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,500,1968
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 1200 nmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 346,129,1995
 
                            *** END OF RECORD ***