*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XT5160000
CHEMICAL NAME           : p-Toluenesulfonamide,
                          N-(5-amino-1-(chloroacetyl)pentyl)-, hydrochloride,
                          L-
CAS REGISTRY NUMBER     : 4272-74-6
LAST UPDATED            : 199707
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H21-Cl-N2-O3-S.Cl-H
MOLECULAR WEIGHT        : 369.34
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * L-N-(5-Amino-1-(chloroacetyl)pentyl)-p-toluenesulfonamide hydrochloride
   * Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-,  
   monohydrochloride, (S)-
   * TLCK hydrochloride
   * N-alpha-p-Tosyl-L-lysine chloromethyl ketone hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravaginal
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 150 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 19,95,1979
 
                            *** END OF RECORD ***